Tag Archives: psychedelic drugs for mental illness

May 29, 2022 · 1:00 am

Psychedelics for Anxiety, Depression, and PTSD, Part 2

File:FerndalePoliceStop102415.jpg

Drug paraphernalia including marijuana/cannabis and a methamphetamine pipe, following a police stop in Ferndale, CA, Author Ferndale Police Dept., Source https://kymkemp.com
(PD per California Public Records Act)

We continue our discussion of the risks and benefits of a drug-based psychiatric approach utilizing psychedelics to treat anxiety, depression, and post-traumatic stress disorder (PTSD).

Despite growing enthusiasm for the use of psychedelics, the evidence is far from in.

LSD

Lysergic acid diethylamide (LSD) – one of the most potent hallucinogens – was studied from the 1950s to 1970s in order to assess behavioral and personality changes, as well as relief from psychiatric symptoms [1][2A].

LSD was originally used in the treatment of anxiety, depression, addiction, and psychosomatic illness.  Readers may recall that the US Army and CIA, also, experimented with LSD as a truth serum.  But most early studies were not performed to today’s standards.

Across 11 randomized-controlled studies (involving a combined total of 567 patients) positive outcomes were observed, particularly with regard to alcoholism [2B].

In rare instances, however, psychedelics such as psilocybin and LSD can evoke a lasting psychotic reaction (more frequently in patients with a family history of psychosis) [3A].  Adequate screening of a patient’s vulnerability and prior psychotic episodes before the use of LSD is, therefore, emphasized. Continue reading →

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May 22, 2022 · 1:00 am

Psychedelics for Anxiety, Depression, and PTSD, Part 1

File:Ecstasy monogram.jpg

Ecstacy a/k/a Molly, Author DEA, Source https://www.dea.gov, (PD as work product of federal govt.)

“I am more convinced than ever that psychiatric medications, over the long term, cause net harm.  I wish that weren’t the case, but the evidence just keeps mounting that these drugs, on the whole, worsen long-term outcomes…The inventor of frontal lobotomy…was awarded a Nobel Prize for inventing that surgery, which today we understand as a mutilation.”

-Award-winning science author and journalist, Robert Whitaker [1][2]

Recently, a number of drug trials have been conducted re-assessing the effectiveness of psychedelics for anxiety, depression, and post-traumatic stress disorder (PTSD).

While the results of these trials have been heralded as providing new treatment options for tenacious illnesses, there are serious dangers associated with psychedelics.

Serotonin

Psychedelics act on receptors in the brain for serotonin, a neurotransmitter that effects mood.

There is some thinking that psychedelics enhance the brain’s capacity to form and reorganize synaptic connections, especially following injury [3A].  But this hypothesis needs further research.

In the therapeutic setting, psychedelics cause a receptive, dream-like state during which memories are readily accessible [3B].  The theory is that this state opens the door to fresh ideas the therapist can introduce.

Unsupervised use is not recommended. Continue reading →

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