Monthly Archives: December 2025

Editing the Human Genome

Double helix of DNA biochemistry, Author brian0918&#153 (PD)

Editing the human genome is no longer beyond the realm of possibility.  To the contrary, it represents the frontier of medicine, promising a golden future without heritable disease or genetic defects.  The question is:  at what cost to human rights?

Human genome editing takes two forms:  somatic genome editing (which modifies non-reproductive cells) and germline genome editing (which modifies reproductive cells, including sperm and egg cells, and can be passed on to future generations) [1A].

Somatic Gene Editing

Somatic gene editing is viewed as less controversial, since it cannot be passed on.  The United States, the United Kingdom, and China have all permitted clinical trials involving somatic editing to treat cancer, sickle cell anemia, and other genetic diseases [1B].

Germline Gene Editing

No country has yet approved germline genetic editing, although twins whose germline had been modified using the genetic cut-copy-paste technology known by the acronym CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) were born in China in 2018 [1C][2A]. 

A majority of the European Union has ratified the Oviedo Convention which prohibits heritable gene editing in humans [1D].  Germany, Canada, and Australia have adopted similar prohibitions [1E].  

There is a strong possibility that these bans will eventually be lifted for therapeutic purposes, though there is no current agreement on what qualifies as “therapeutic”.  There is an equal chance that access to germline genetic editing will at some point be characterized as a legal “right” [6A].

In the United States, law currently prohibits the use of federal funds on human germline gene therapy [2B].  However, there are no protocols or restrictions for human genomic engineering [2C]. 

Recently, a startup named Preventive was identified as attempting to engineer the first genetically modified baby outside China [3].  This is not surprising, since Do-It-Yourself CRISPR kits are actually available online [6B]. Continue reading

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Good Tidings

“Nativity of Christ a/k/a Holy Night” by Antonio de Correggio (c. 1529-1530), Staatliche Kunstsammlungen (Accession No. Gal.-Nr. 152), Dresden, Source/Photographer Google Arts & Culture https://artsandculture.google.com/asset/7wGhio0LPVXb_g Hans Peter Klut/Elke Estel (PD)

Then the angel said to them, ‘Do not be afraid, for behold, I bring you good tidings of great joy which will be to all people.  For there is born to you this day in the city of David a Savior, who is Christ the Lord.  And this will be the sign to you: You will find a Babe wrapped in swaddling cloths, lying in a manger’” (Luke 2: 10-12).

Wishing you all a Merry Christmas!

FOR MORE OF MY ARTICLES ON POVERTY, POLITICS, AND MATTERS OF CONSCIENCE CHECK OUT MY BLOG A LAWYER’S PRAYERS AT: https://alawyersprayers.com

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Climbing Gear

Open crevasse, Tangra Mountains, Antarctica, Author Apcbg, (CC BY-SA 4.0 International)

A chasm opens up again.  Depression yawns before us once more, sucking us in despite our best efforts.

It may be that something reminded us of our earlier trauma.  It may be that regret over an old loss or error in judgment morphed from sadness into despair.  Whatever the cause, as abuse victims we can suddenly find ourselves falling headlong into darkness. 

Consumed with self-loathing, we may feel achingly alone in a crowd, strangers in a strange land while at a local mall or familiar church service. 

The greetings, compliments, and good wishes of loved ones – however many, however sincere – are dismissed as undeserved.  Life loses its savor.  Even prayer seems stale.

Surprisingly, the skills and equipment necessary to alpine rescue have bearing on this.

Fatal Self-Isolation

Engulfed by depression, our instinct will likely be to self-isolate.  But this can be a fatal mistake, effectively putting us at risk of hypothermia from the cold of the mountain crevasse into which we have fallen. 

It can take a rescue team and specialized equipment to pull a climber who has fallen into such a crevasse back to safety.

Climbing Team

It is essential to remember that none of us really climbs the mountains of life alone.  We are all linked to others – to family, friends, roommates, neighbors, teachers, classmates, coaches, teammates, co-workers, health care providers, crisis hot lines, and God, Himself.  These are vital resources. Continue reading

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In Search of Greatness

Woodcut “Jesus Teaches Greatness” from “Die Bibel in Bildern” (“The Bible in Pictures”) by Julius Schnorr von Carolsfeld (1860), Source “Die Bibel in Bildern” (“The Bible in Pictures”), (PD) 

I dreamt last night of a frustrated young man, longing for meaning and purpose.  For greatness, as the world defines it.

But greatness is not defined by the billions garnered overnight for a clever idea at the right moment, or – more often, these days – a mirage sold to a public so hungry for something of substance it will swallow almost anything.  Greatness is not exemplified by Apple or Twitter or Lululemon, no matter how high their stock price.

Greatness is exemplified by the daily faithfulness of a good father working a menial job to put food on the table and shoes on his children’s feet, by the daily patience of a good mother homeschooling an autistic child for lack of a better alternative.

Greatness is not measured in moments.  It is measured across a lifetime.

Few of us are called to go out in a blaze of cinematic glory, applauded martyrs to a popular cause.  More are called to stand guard on lonely frontiers, to push boulders endlessly up impossible hills, our worth unrecognized and unsung.

God sees those efforts, nonetheless.  It is He who assigns their true value, not this deluded, transient world.  It is urgent our young people hear this from us.

But he who is greatest among you shall be your servant” (Matt. 23: 11).

FOR MORE OF MY ARTICLES ON POVERTY, POLITICS, AND MATTERS OF CONSCIENCE CHECK OUT MY BLOG A LAWYER’S PRAYERS AT:  https://alawyersprayers.com

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